John Henry, lead vocalist and guitarist, sings late Friday night at Beer:30, 4th and Merchant streets. The band is planning a tour of Europe in 2010. Jennifer Baldwin/The Bulletin.
On Friday, John Henry and the Engine performed onstage at Beer:30. The St. Louis/ Columbia, Mo based band is touring about 100-110 dates a year and has had shows in Emporia for the past few years.
“We’ve been playing in Emporia for about two years off and on,” guitarist and vocalist John Henry said, “more on lately. We were introduced to the scene by Ha Ha Tonka. They just showed us this market here in Kansas and it was pretty close to home and the people cared about live music, so that’s why we’re here.”
The band classifies itself as “Americana” music and keyboardist and vocalist Wes Wingate said their influence is American music of all kinds, including country, soul, gospel and rock and roll. At the show, they played covers of Credence Clearwater Revival.
“You know, the stuff they’re doing is pretty late 60s-esque stuff,” said John Shell, music major. “I mean, it is what it is and they play it very well. When you do covers, you want to hear somebody that can nail it.”
Henry and Wingate said they like playing in Emporia because there’s always a crowd of people that care about the music.
“The best thing about Emporia is probably the fact that there ain’t much to do in Emporia,” Wingate said. “So we are gathered here and everybody who is going to be out tonight is going to be here, really and that centralizes it which is harder.
“The bigger the city, the more it’s like a hotdog down a hallway, but here we can just really get a lot of people at once. And you know that they’re going to care about what you’re doing most of the time, so that’s a really good quality of this town.”
Eric Nelson, a member of The Whiskey Trio, which opened for John Henry, said he was honored to open for a band that the crowd really enjoyed.
“I thought it was great,” Nelson said. “It’s nice that there’s touring musicians coming to Emporia that care enough to stop here. It’s just good that we have musicians from other parts of the country coming through here.”
John Henry and the Engine plan on touring Europe in 2010. They are also coming out with a new EP on vinyl in October and will be back in Emporia towards the end of that month.
“The goals that we have are to constantly write better songs and to expand the radius that we tour in and to build up so that everyone can hear us,” Henry said. “We want people to hear the music that we do because we feel like what we’re doing is honest American music and we’re not trying to bullshit anybody.”
Lauren Walbridge/The Bulletin
Fexofenadine, loratadine supported for reactions, but not chlorpheniramine.
Clinical Trials Week January 27, 2003 2003 JAN 27 – (NewsRx.com & NewsRx.net) — “The extent of the distribution of H-1-antihistamines into the skin and H-1-antihistamine activity in the skin are clinically relevant in the treatment of allergic skin disorders,” researchers in Canada report.
“In a prospective, randomized, double blind, parallel group, multiple dose study, we gave fexofenadine 180 mg, loratadine 10 mg, or chlorpheniramine 8 mg to 21 men (7 in each group). Before dosing and at 1, 3, 6, 9, and 24 hours after the first antihistamine dose as well as at 168, 192, and 216 hours after the first dose (12, 36, and 60 hours after the seventh and last consecutive daily H-1-antihistamine dose), we measured fexofenadine, loratadine, or chlorpheniramine concentrations in plasma and in skin tissue samples obtained through use of punch biopsies, along with suppression of histamine induced skin wheals and flares. in our site loratadine side effects
“Loratadine metabolites, including desloratadine and its metabolites, were not measured, and chlorpheniramine metabolites were not measured,” wrote F.E.R. Simons and colleagues, Winnipeg.
The researchers found that “all 21 participants completed the study. Skin/plasma fexofenadine ratios ranged from 1.2[+ or -]0.5 at 1 hour to 110[+ or -]74 at 24 hours, and skin fexofenadine concentrations exceeded loratadine and chlorpheniramine skin concentrations at each test time. This was reflected in significant wheal and flare suppression by fexofenadine in comparison with loratadine at 3 hours and in comparison with chlorpheniramine at 6 hours and 9 hours (wheal), and from 3-24 hours and at 192 hours (flare).
“Compared with fexofenadine, loratadine significantly suppressed the wheal at 192 hours, and compared with chlorpheniramine, it significantly suppressed the wheal at 9 hours and the flare at 24 and 192 hours. At no time did chlorpheniramine suppress the wheal or flare significantly more than fexofenadine or loratadine.” The researchers concluded: “In skin disorders for which H-1-antihistamines are recommended, these results support the use of fexofenadine or loratadine, and they indicate the need for reexamination of the use of chlorpheniramine.” Simons and colleagues published their study in Journal of Allergy and Clinical Immunology (Clinical pharmacology of H-1-antihistamines in the skin. J Allergy Clin Immunol, 2002;110(5):777-783). website loratadine side effects
The contact person for this report is F.E.R. Simons, 820 Sherbrook St., Winnipeg, MB R3A 1R9, Canada.
To subscribe to the Journal of Allergy and Clinical Immunology, contact the publisher: Mosby, Inc., 11830 Westline Industrial Dr., St. Louis, MO 63146-3318 USA.
The information in this article comes under the major subject areas of Allergy Medicine, Dermatology and Pharmacology.
This article was prepared by Clinical Trials Week editors from staff and other reports.
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